What does the anion gap tell you?
The anion gap blood test is used to show whether your blood has an imbalance of electrolytes or too much or not enough acid. Too much acid in the blood is called acidosis. If your blood does not have enough acid, you may have a condition called alkalosis.
What is a high anion gap?
An anion gap is usually considered to be high if it is over 12 mEq/L. High anion gap metabolic acidosis is typically caused by acid produced by the body. More rarely, it may be caused by ingesting methanol or overdosing on aspirin.
What is a healthy anion gap?
Healthy subjects typically have a gap of 0 to slightly normal (< 10 mEq/L). A urine anion gap of more than 20 mEq/L is seen in metabolic acidosis when the kidneys are unable to excrete ammonia (such as in renal tubular acidosis).
What are symptoms of low anion gap?
Conditions associated with a low anion gap are unlikely to cause symptoms . A person with acidosis may not experience any symptoms or may have nonspecific symptoms related to the underlying medical condition, such as: nausea or vomiting. fatigue. a headache. drowsiness. shortness of breath . rapid heart rate. low blood pressure.
How do you treat high anion gap?
The most common alkalizing agent is sodium bicarbonate, but sodium and potassium citrate are alternative options. In the event of severe, recalcitrant acidosis, it may be appropriate to treat empirically with alcohol dehydrogenase inhibitors (fomepizole or ethanol) and prepare the patient for emergent hemodialysis.
Should I be concerned about a low anion gap?
If you really do have a low anion gap , it could mean your blood doesn’t have enough of a protein called abumin. That can be a sign of conditions like: Kidney problems. Heart disease.
What foods cause acidosis?
Diets high in salt, soda, and animal protein can cause acidosis . People can moderate their intake of these foods and increase their daily intake of fruits and vegetables.
Can dehydration cause acidosis?
Metabolic acidosis occurs in dehydrated patients with gastroenteritis; there are multiple causes of this acidosis . 1-5 It is generally believed that acidosis , equated with a reduced concentration of bicarbonate in serum, reflects the severity of dehydration , although no study substantiating this has been found.
Can alcohol cause anion gap?
Alcohol diminishes hepatic gluconeogenesis and leads to decreased insulin secretion, increased lipolysis, impaired fatty acid oxidation, and subsequent ketogenesis, causing an elevated anion gap metabolic acidosis.
Is an anion gap of 6 bad?
The normal (physiologic) range of the anion gap was defined as 6 -14 mEq/L, and an anion gap >14.1 mEq/L was considered high.
What is CO2 in blood work?
The CO2 blood test measures the amount of carbon dioxide in the blood , which is present in the form of CO2 , bicarbonate (HCO3), and carbonic acid (H2CO3). It mainly occurs in the form of bicarbonate. As part of its normal functions, the human body naturally produces certain acids and bases that balance each other.
What is Agap in blood work?
Anion gap (AG or AGAP ) is a value calculated using the results of an electrolyte panel. It is used to help distinguish between anion-gap and non-anion-gap metabolic acidosis.
What is considered a low anion gap?
Results: Based on current clinical data, an anion gap value of < 3 mEq/L should be considered low . A low anion gap is a useful diagnostic tool, but its clinical significance is often unrecognized.
What is the reason for low albumin?
Hypoalbuminemia can be caused by various conditions, including nephrotic syndrome, hepatic cirrhosis , heart failure , and malnutrition; however, most cases of hypoalbuminemia are caused by acute and chronic inflammatory responses. Serum albumin level is an important prognostic indicator.
What is a closed anion gap?
In the hospital setting, you may hear the phrase “the anion gap is closed .” This often refers to the patient who is admitted to the hospital with ketoacidosis from uncontrolled diabetes. Typically, IV fluids and an insulin drip are administered until the gap is closed , and then a maintenance regimen may begin.